“ROLE OF VRANA SHODHANA AND VRANA ROPANA DRAVYAS IN CHRONIC WOUND MANAGEMENT: AN AYURVEDIC AND MODERN PERSPECTIVE”
Introduction: Chronic wounds such as diabetic ulcers, venous ulcers, and pressure sores pose significant challenges in modern healthcare due to prolonged healing time, infection, and recurrence. Ayurveda describes wound management under Shalya Tantra, emphasizing the roles of Vrana Shodhana (cleansing agents) and Vrana Ropana (healing agents). These therapeutic categories provide both local and systemic approaches for chronic wound care. Methods: A comprehensive literature review was conducted using Ayurvedic classical texts (Sushruta Samhita, Charaka Samhita, Ashtanga Hridaya), contemporary commentaries, and databases including PubMed, Scopus, and Web of Science. Articles published between 1980–2025 were screened. Inclusion criteria were studies focusing on Ayurvedic formulations, pharmacological validation, and clinical trials related to chronic wound healing. Exclusion criteria were anecdotal reports and non-peer-reviewed sources. Results: Classical literature identifies numerous herbs such as Haridra (Curcuma longa), Nimba (Azadirachta indica), Jati (Jasminum officinale), and Madhu (honey) with Vrana Shodhana and Ropana properties. Modern studies validate their antimicrobial, antioxidant, and tissue-regenerative activities. Formulations like Jatyadi Taila, Panchavalkala Kwatha, and Honey-based dressings have shown significant benefits in wound debridement, infection control, and epithelialization. Clinical trials support the efficacy of Jatyadi Taila and Madhu in managing diabetic foot ulcers and non-healing wounds. Discussion: Ayurveda’s dual approach of cleansing and healing parallels modern wound bed preparation and regenerative therapies. While modern medicine emphasizes antibiotics, surgical debridement, and advanced dressings, Ayurvedic agents provide natural, cost-effective, and synergistic options. However, standardized clinical validation and integration with modern wound care protocols remain necessary. Conclusion: Vrana Shodhana and Vrana Ropana dravyas hold significant promise in chronic wound management, bridging classical wisdom and modern validation. They offer effective, affordable, and holistic strategies that can complement current therapeutic approaches.
KEYWORDS: Ayurveda, Chronic wounds, Vrana Ropana, Vrana Shodhana, Wound healing